Efficacy and tolerability of valsartan in combination with hydrochlorothiazide in essential hypertension.

@article{Hall1998EfficacyAT,
  title={Efficacy and tolerability of valsartan in combination with hydrochlorothiazide in essential hypertension.},
  author={Wayne D Hall and Rafael Montoro and T Littlejohn and Aditya M Jain and Nancy Feliciano and Hongjie Zheng},
  journal={Clinical drug investigation},
  year={1998},
  volume={16 3},
  pages={203-10}
}
OBJECTIVE This study compared the efficacy and tolerability of two combination regimens of valsartan and hydrochlorothiazide (HCTZ) with valsartan monotherapy in patients with essential hypertension inadequately controlled with valsartan 80mg once daily. PATIENTS AND METHODS A total of 708 patients with inadequately controlled blood pressure after 4 weeks' treatment with valsartan 80mg once daily participated in this double-blind comparative trial. Patients were randomly allocated once-daily… CONTINUE READING