Efficacy and tolerability of loratadine versus fexofenadine in the treatment of seasonal allergic rhinitis: a double-blind comparison with crossover treatment of nonresponders.

@article{Prenner2000EfficacyAT,
  title={Efficacy and tolerability of loratadine versus fexofenadine in the treatment of seasonal allergic rhinitis: a double-blind comparison with crossover treatment of nonresponders.},
  author={Bruce M. Prenner and D Capano and Alan G. Harris},
  journal={Clinical therapeutics},
  year={2000},
  volume={22 6},
  pages={760-9}
}
BACKGROUND Nonsedating antihistamines are well-established treatment for seasonal allergic rhinitis (SAR), but patients do not always respond to the first antihistamine prescribed. OBJECTIVE This double-blind, double-dummy, randomized, 2-phase, multicenter study was designed primarily to compare the therapeutic responses to loratadine and fexofenadine in patients who failed initial therapy with the other drug. METHODS Male and female patients aged 12 to 60 years received loratadine 10 mg… CONTINUE READING