Efficacy and tolerability of controlled-release trazodone in depression: a large multicentre study in general practice.

@article{Moon1990EfficacyAT,
  title={Efficacy and tolerability of controlled-release trazodone in depression: a large multicentre study in general practice.},
  author={Charles A L Moon and David Joseph Laws and Pamela Stott and Gregory Hayes},
  journal={Current medical research and opinion},
  year={1990},
  volume={12 3},
  pages={
          160-8
        }
}
A double-blind, parallel-group study was carried out to compare the efficacy and tolerability of a controlled-release tablet formulation of trazodone with the standard trazodone tablet. Three hundred and forty-seven general practice patients with depressive symptoms were recruited into the trial. Patients were randomly allocated to receive either 1 controlled-release trazodone (150 mg) tablet at night or 1 standard trazodone (150 mg) tablet at night for a period of 6 weeks. Assessments of… CONTINUE READING