Efficacy and tolerability of combination therapy with valsartan/hydrochlorothiazide in the initial treatment of severe hypertension.

@article{Calhoun2008EfficacyAT,
  title={Efficacy and tolerability of combination therapy with valsartan/hydrochlorothiazide in the initial treatment of severe hypertension.},
  author={David A. Calhoun and Robert D. Glazer and Frank S Pettyjohn and Pieter Coenen and Yanxing Zhao and Amie Grosso},
  journal={Current medical research and opinion},
  year={2008},
  volume={24 8},
  pages={2303-11}
}
OBJECTIVE Most patients with severe hypertension are at high risk for cardiovascular events and require prompt blood pressure (BP)-lowering and combination therapy to achieve BP goals. This study evaluated the therapeutic efficacy and tolerability of initial treatment with the combination of valsartan and hydrochlorothiazide (HCTZ) compared with valsartan… CONTINUE READING