Efficacy and tolerability of botulinum toxin type A in patients with neurogenic detrusor overactivity and without concomitant anticholinergic therapy: comparison of two doses.

@article{Grise2010EfficacyAT,
  title={Efficacy and tolerability of botulinum toxin type A in patients with neurogenic detrusor overactivity and without concomitant anticholinergic therapy: comparison of two doses.},
  author={Philippe Grise and Alain Ruffion and Pierre Denys and Guy Egon and Emmanuel Chartier Kastler},
  journal={European urology},
  year={2010},
  volume={58 5},
  pages={759-66}
}
BACKGROUND Botulinum toxin type A (BoNTA) has been reported to be effective for treatment of patients with neurogenic detrusor overactivity (NDO) refractory to anticholinergic agents. However, in most of the studies, the efficacy was associated with concomitant use of anticholinergics. OBJECTIVE To evaluate the efficacy and tolerability of BoNTA and compare two different doses in patients with NDO without concomitant anticholinergics. DESIGN, SETTING, AND PARTICIPANTS Between 2004 and 2006… CONTINUE READING
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