Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis.

@article{Beghi1995EfficacyAT,
  title={Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis.},
  author={G Beghi and F Berni and Luigi Carrat{\'u} and Angelo Gianni Casalini and Giorgio Consigli and M D'Ant{\`o} and V. Gioia and A M Molino and Georgina Paizis and Adriano Vaghi},
  journal={Journal of chemotherapy},
  year={1995},
  volume={7 2},
  pages={146-52}
}
An open randomized trial was conducted in 142 hospitalized and out-patients with acute purulent exacerbation of chronic bronchitis to compare the clinical efficacy and tolerability of azithromycin (n = 69) and amoxicillin/clavulanic acid (n = 73). Azithromycin (500 mg) was administered as a single dose for three days and amoxicillin/clavulanic acid (amoxicillin 875 mg-clavulanic acid 125 mg) was given b.i.d. for 8 days (8.16 +/- 1.18). Before therapy and 24-48 hours after the end of treatment… CONTINUE READING

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