Efficacy and tolerability of 5-aminolevulinic acid 0.5% liposomal spray and intense pulsed light in wrinkle reduction of photodamaged skin.

@article{Piccioni2011EfficacyAT,
  title={Efficacy and tolerability of 5-aminolevulinic acid 0.5% liposomal spray and intense pulsed light in wrinkle reduction of photodamaged skin.},
  author={Antonella Piccioni and Maria Concetta Fargnoli and Spyridon Schoinas and M Suppa and Pasquale Frascione and Agnese Ginebri and Sergio Chimenti and Ketty Peris},
  journal={The Journal of dermatological treatment},
  year={2011},
  volume={22 5},
  pages={247-53}
}
BACKGROUND Photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA) is effective for the treatment of photoaging. OBJECTIVE To evaluate the efficacy and safety of PDT using a novel 0.5% liposome-encapsulated 5-ALA spray and an intense pulsed light (IPL) system (Ellipse Flex PPT) in reduction of periorbital and nasolabial wrinkles. PATIENTS AND METHODS Thirty healthy volunteers, aged 35-65 years, skin type I-III, with type 2 photoaging underwent a baseline visit, three ALA-IPL… CONTINUE READING