Efficacy and temporal stability of reduced safety margins for ventricular defibrillation: primary results from the Low Energy Safety Study (LESS).

@article{Gold2002EfficacyAT,
  title={Efficacy and temporal stability of reduced safety margins for ventricular defibrillation: primary results from the Low Energy Safety Study (LESS).},
  author={Michael R Gold and Steven Higgins and Richard Klein and Francis Roosevelt Gilliam and Harry Kopelman and Scott E. Hessen and John Payne and S. Adam Strickberger and David J Breiter and Stephen Hahn},
  journal={Circulation},
  year={2002},
  volume={105 17},
  pages={2043-8}
}
BACKGROUND Traditionally, a safety margin of at least 10 J between the maximum output of the pulse generator and the energy needed for ventricular defibrillation has been used because lower safety margins were associated with unacceptably high rates of failed defibrillation and sudden cardiac death. The Low Energy Safety Study (LESS) was a prospective, randomized assessment of the safety margin requirements for modern implantable cardioverter-defibrillator (ICD) systems. METHODS AND RESULTS A… CONTINUE READING

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Circulation. 2001;104:II-654. Abstract • 2001

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