Efficacy and safety profile of imatinib mesylate (ST1571) in Japanese patients with advanced gastrointestinal stromal tumors: a phase II study (STI571B1202)

@article{Nishida2007EfficacyAS,
  title={Efficacy and safety profile of imatinib mesylate (ST1571) in Japanese patients with advanced gastrointestinal stromal tumors: a phase II study (STI571B1202)},
  author={Toshirou Nishida and Kuniaki Shirao and Akira Sawaki and Masato Koseki and Takeshi Okamura and Atsushi Ohtsu and Toshiro Sugiyama and Kunihisa Miyakawa and Seiichi Hirota},
  journal={International Journal of Clinical Oncology},
  year={2007},
  volume={13},
  pages={244-251}
}
Imatinib mesylate, an inhibitor of KIT, ABL protein, and platelet-derived growth factor receptor α (PDGFRα) tyrosine kinase, has recently been found to have a dramatic antitumor effect on gastrointestinal stromal tumor (GIST). The aim of this study was to assess the efficacy and safety of imatinib mesylate in Japanese patients with advanced GIST. Patients with measurable lesions were enrolled between April 1, 2002, and September 20, 2002, using a design based on previous phase II studies in the… CONTINUE READING

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References

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Showing 1-10 of 22 references

Long-term follow-up of a phase II randomized trial in advanced gastrointestinal stromal tumor (GIST) patients treated with imatinib mesylate

  • CD Blanke, GD Demetri, MV Mehren
  • J Clin Oncol 24:18S (Suppl;
  • 2006
Highly Influential
7 Excerpts

Effi cacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

  • GD Demetri, M von Mehren, CD Blanke
  • N Engl J Med
  • 2002
Highly Influential
9 Excerpts

Effi cacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

  • GD Demetri, AT van Oosterom, CR Garrett
  • Lancet
  • 2006
1 Excerpt

Long - term follow - up of a phase II randomized trial in advanced gastrointestinal stromal tumor ( GIST ) patients treated with imatinib mesyl

  • CD Blanke, GD Demetri, MV Mehren
  • J Clin Oncol
  • 2006

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