Corpus ID: 30475972

Efficacy and safety of willow bark extract in the treatment of osteoarthritis and rheumatoid arthritis: results of 2 randomized double-blind controlled trials.

@article{Biegert2004EfficacyAS,
  title={Efficacy and safety of willow bark extract in the treatment of osteoarthritis and rheumatoid arthritis: results of 2 randomized double-blind controlled trials.},
  author={Claudia Biegert and Irmela Wagner and Rainer L{\"u}dtke and Ina K{\"o}tter and C Lohm{\"u}ller and Ilhan G{\"u}naydın and Katja Taxis and Lutz Heide},
  journal={The Journal of rheumatology},
  year={2004},
  volume={31 11},
  pages={
          2121-30
        }
}
OBJECTIVE To investigate the efficacy and safety of a standardized willow bark extract in patients with osteoarthritis (OA) and rheumatoid arthritis (RA). METHODS We studied 127 outpatients with hip or knee OA and a WOMAC pain score of at least 30 mm and 26 outpatients with active RA in 2 randomized, controlled, double-blind trials with followup for 6 weeks. OA trial: Patients were randomized to receive willow bark extract, corresponding to 240 mg of salicin/day, diclofenac 100 mg/day, or… Expand
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