Efficacy and safety of twice- vs once-daily dosing of lisinopril for hypertension.

@article{Tsai2017EfficacyAS,
  title={Efficacy and safety of twice- vs once-daily dosing of lisinopril for hypertension.},
  author={Tiffany Tsai and Miranda Kroehl and Steven M Smith and Angela Myers Thompson and Isabella Y Dai and Katy E Trinkley},
  journal={Journal of clinical hypertension},
  year={2017},
  volume={19 9},
  pages={
          868-873
        }
}
This retrospective cohort study compared administration of lisinopril twice daily and once daily for hypertension. Data were collected from an ambulatory electronic health record between 2011 and 2014. Patients previously receiving lisinopril 20 mg were placed into the once-daily cohort if changed to 40 mg once daily or into the twice-daily cohort if changed to 20 mg twice daily. Efficacy outcome measures were change in systolic blood pressure and diastolic blood pressure and achievement of… CONTINUE READING
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