Efficacy and safety of transarterial chemoembolization plus sorafenib for early or intermediate stage hepatocellular carcinoma: A systematic review and meta-analysis of randomized controlled trials.

@article{Zeng2016EfficacyAS,
  title={Efficacy and safety of transarterial chemoembolization plus sorafenib for early or intermediate stage hepatocellular carcinoma: A systematic review and meta-analysis of randomized controlled trials.},
  author={Jian Zeng and Lin Lv and Zhe-chuan Mei},
  journal={Clinics and research in hepatology and gastroenterology},
  year={2016},
  volume={40 6},
  pages={
          688-697
        }
}
BACKGROUND AND AIM The efficacy and safety of transarterial chemoembolization (TACE) plus sorafenib for patients with hepatocellular carcinoma (HCC) have been explored by many studies, but the results were controversial. Therefore, we performed this meta-analysis of high-quality randomized controlled trials to evaluate the efficacy and safety of TACE plus sorafenib versus TACE monotherapy in the early or intermediate stage HCC. METHODS Multi-databases were systematically searched to identify… CONTINUE READING

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