Efficacy and safety of topical application of human fibrinogen/thrombin-coated collagen patch (TachoComb) for treatment of air leakage after standard lobectomy.

@article{Lang2004EfficacyAS,
  title={Efficacy and safety of topical application of human fibrinogen/thrombin-coated collagen patch (TachoComb) for treatment of air leakage after standard lobectomy.},
  author={Irene M. Lang and Attila Cseke{\"o} and Georgios Stamatis and Ludwig H Lampl and Leif Hagman and Gabriel Mihai Marta and Michael R. Mueller and Walter Klepetko},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2004},
  volume={25 2},
  pages={
          160-6
        }
}
OBJECTIVES Persisting air leakage after pulmonary resection remains a significant problem. The aim of the study was to evaluate the incidence of air leakage after standard lobectomy and test the efficacy and safety of TachoComb (TC). METHODS A total of 189 patients undergoing lobectomy were enrolled in a multi-centre, open, randomised, and prospective study to test the efficacy and safety of TachoComb (TC) for air leakage treatment. Air leakage was assessed by water submersion test, and… CONTINUE READING
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