Efficacy and safety of the pulsed infusions of levosimendan in outpatients with advanced heart failure (LevoRep) study: a multicentre randomized trial.

@article{Altenberger2014EfficacyAS,
  title={Efficacy and safety of the pulsed infusions of levosimendan in outpatients with advanced heart failure (LevoRep) study: a multicentre randomized trial.},
  author={Johann Altenberger and J. Parissis and Angelika Costard-Jaeckle and Andreas Winter and Christian Ebner and Apostolos J Karavidas and Kurt Sihorsch and Ekaterini Avgeropoulou and Thomas Weber and Lida Dimopoulos and Hanno Ulmer and Gerhard Poelzl},
  journal={European journal of heart failure},
  year={2014},
  volume={16 8},
  pages={898-906}
}
AIMS The aim of this study was to determine whether intermittent ambulatory treatment with levosimendan would improve functional capacity, quality of life, and event-free survival in patients with advanced heart failure. METHODS AND RESULTS This was a prospective, randomized, double-blind, placebo-controlled, multicentre, parallel-group trial of pulsed infusions of levosimendan in 120 outpatients with advanced heart failure (EF ≤35%, NYHA class III or IV). The study was conducted at 11… CONTINUE READING
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