Efficacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with type 2 diabetes mellitus.

@article{Scheen2010EfficacyAS,
  title={Efficacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with type 2 diabetes mellitus.},
  author={Andr{\'e} Scheen and Guillaume Charpentier and Carl Johan Ostgren and Asa Hellqvist and Ingrid A M Gause-Nilsson},
  journal={Diabetes/metabolism research and reviews},
  year={2010},
  volume={26 7},
  pages={540-9}
}
BACKGROUND Dipeptidyl peptidase-4 inhibitors improve glycaemic control in patients with type 2 diabetes mellitus when used as monotherapy or in combination with other anti-diabetic drugs (metformin, sulphonylurea, or thiazolidinedione). This 18-week, phase 3b, multicentre, double-blind, noninferiority trial compared the efficacy and safety of two dipeptidyl peptidase-4 inhibitors, saxagliptin and sitagliptin, in patients whose glycaemia was inadequately controlled with metformin. METHODS… CONTINUE READING
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  • Aguilar-Salinas C Klein E Nepal S List J Chen R. Effect of saxagli Rosenstock J, 25
  • Published in : Diabetes/Metabolism Research…
  • 2010
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