Efficacy and safety of rosuvastatin in the management of dyslipidemia

@article{Rubba2009EfficacyAS,
  title={Efficacy and safety of rosuvastatin in the management of dyslipidemia},
  author={Paolo Rubba and Gennaro Marotta and Marco Gentile},
  journal={Vascular Health and Risk Management},
  year={2009},
  volume={5},
  pages={343 - 352}
}
Rosuvastatin is a synthetic statin that represents an advance in the pharmacologic and clinical properties of statins. Relative to other statins, rosuvastatin possesses a greater number of binding interactions with HMG-CoA reductase and has a high affinity for the active site of the enzyme. As with other statins, serious adverse effects with rosuvastatin therapy are uncommon and primarily involve effects on the liver and skeletal muscle. The risk increases with increasing dosages and… CONTINUE READING

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