Efficacy and safety of pegylated interferon in children and adolescents infected with chronic hepatitis C: a preliminary study.

@article{AbdelAziz2011EfficacyAS,
  title={Efficacy and safety of pegylated interferon in children and adolescents infected with chronic hepatitis C: a preliminary study.},
  author={Doa'a Hamed Abdel-Aziz and Nirmeen Ahmed Sabry and Manal Hamdy El-Sayed and Omima Naiem El-Gazayerly},
  journal={Journal of pharmacy practice},
  year={2011},
  volume={24 2},
  pages={
          203-10
        }
}
This study researches the efficacy and safety of pegylated interferon alpha-2a (pegIFNα-2a) in Egyptian children and adolescents diagnosed with hepatitis C virus. Thirty patients were enrolled to receive pegIFN once a week with ribavirin twice daily for 12 weeks; viral load and experienced adverse effects were then assessed. Of the 30 patients, 16 (53.33%) were cleared from the virus, showing early virologic response (EVR). Three patients (10%) showed a 2-log reduction by week 12, with an… CONTINUE READING
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