Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review.

@article{Bouza2004EfficacyAS,
  title={Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review.},
  author={Carmen Bouza and M {\'A}ngeles and Ana Bel{\'e}n Jim{\'e}nez Mu{\~n}oz and Jos{\'e} Mar{\'i}a Amate},
  journal={Addiction},
  year={2004},
  volume={99 7},
  pages={
          811-28
        }
}
  • Carmen Bouza, M Ángeles, +1 author José María Amate
  • Published in Addiction 2004
  • Medicine
  • AIMS To ascertain the efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence. METHODS Systematic review of the literature (1990-2002) and meta-analysis of full published randomized and controlled clinical trials assessing acamprosate or naltrexone therapy in alcohol dependence. Estimates of effect were calculated according to the fixed-effects model. MEASUREMENTS Relapse and abstinence rates, cumulative abstinence duration and treatment compliance were… CONTINUE READING

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