Efficacy and safety of methotrexate treatment of juvenile localized scleroderma

Abstract

Retrospective study of 59 chlidren with JLS from 3 to 17 y (M = 10.3) treated with MTX was performed. Group 1 (n = 18) – received prednisone 0.5 mg\kg for 6 weeks, taped to 0.1 mg\kg for 12 months + MTX 10 mg\body sq. weekly for 13.7 mo. Group 2 (n = 41) -MTX the same doses and duration. The efficacy was measured in 6 & 12 months using skin score, activity… (More)

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Cite this paper

@inproceedings{Osminina2008EfficacyAS, title={Efficacy and safety of methotrexate treatment of juvenile localized scleroderma}, author={M. K. Osminina and N Geppe and GV Tougarinova and G M Rabieva and Y. O. Kostina}, year={2008} }