Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: results of a 6-month, randomized, comparative trial.

@article{Quattrin2004EfficacyAS,
  title={Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: results of a 6-month, randomized, comparative trial.},
  author={Teresa Quattrin and Andr{\'e} B{\'e}langer and Nancy J. V. Bohannon and Sherwyn L Schwartz},
  journal={Diabetes care},
  year={2004},
  volume={27 11},
  pages={2622-7}
}
OBJECTIVE The aim of this study was to determine whether premeal pulmonary delivery of rapid-acting, dry-powder insulin (Exubera) plus Ultralente could provide glycemic control comparable to a conventional insulin regimen in type 1 diabetes. RESEARCH DESIGN AND METHODS Three hundred thirty-five subjects were randomly assigned to receive either premeal inhaled insulin plus bedtime Ultralente or two to three injections of regular and NPH insulin for 24 weeks. The primary end point was a change… CONTINUE READING
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