Efficacy and safety of fibrin glue and tranexamic acid to prevent postoperative blood loss in total knee arthroplasty: a randomized controlled clinical trial.

@article{Aguilera2013EfficacyAS,
  title={Efficacy and safety of fibrin glue and tranexamic acid to prevent postoperative blood loss in total knee arthroplasty: a randomized controlled clinical trial.},
  author={Xavier Merino Aguilera and Mar{\'i}a Jos{\'e} Mart{\'i}nez-Zapata and Alba Vico Bosch and Gerard Urr{\'u}tia and Juan Carlos Montejo Gonz{\'a}lez and Marcos Jord{\'a}n and Ignasi J. Gich and Rosa Mar{\'i}a Maym{\'o} and Nayeli P{\'a}ez Mart{\'i}nez and Juan Carlos Monllau and Fernando Borda Celaya and Jos{\'e} Antonio Fiz Fern{\'a}ndez},
  journal={The Journal of bone and joint surgery. American volume},
  year={2013},
  volume={95 22},
  pages={
          2001-7
        }
}
BACKGROUND Postoperative blood loss in patients after total knee arthroplasty may cause local and systemic complications and influence clinical outcome. The aim of this study was to assess whether fibrin glue or tranexamic acid reduced blood loss compared with routine hemostasis in patients undergoing total knee arthroplasty. METHODS A randomized, single-center, parallel, open clinical trial was performed in adult patients undergoing primary total knee arthroplasty. Patients were divided into… CONTINUE READING
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