Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.

@article{Davidson2004EfficacyAS,
  title={Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.},
  author={Michael H. Davidson and Christie M. Ballantyne and Boris Kerzner and Lorenzo Melani and Philip T. Sager and Leslie J Lipka and John T. Strony and Ramachandran Suresh and Enrico P Veltri},
  journal={International journal of clinical practice},
  year={2004},
  volume={58 8},
  pages={746-55}
}
We assessed pooled safety and lipid-regulating efficacy data from four similarly designed trials of ezetimibe coadministered with statins in 2382 patients with primary hypercholesterolemia. Patients were randomised to one of the following double-blind treatments for 12 weeks: placebo; ezetimibe 10 mg; statin; or statin + ezetimibe. Statin doses tested were 10, 20, 40 mg/day (atorvastatin, simvastatin, pravastatin or lovastatin) or 80 mg/day (atorvastatin, simvastatin). Treatment with ezetimibe… CONTINUE READING

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