Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study.

@article{Elger2009EfficacyAS,
  title={Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study.},
  author={Christian Erich Elger and P{\'e}ter Hal{\'a}sz and Joana C Maia and Lu{\'i}s Felipe Paes de Almeida and Patr{\'i}cio Soares-da-Silva},
  journal={Epilepsia},
  year={2009},
  volume={50 3},
  pages={454-63}
}
PURPOSE To study the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive therapy for refractory partial seizures in adults with >or=4 partial-onset seizures (simple or complex, with or without secondary generalization) per 4 weeks despite treatment with 1-2 antiepileptic drugs (AEDs). METHODS This multicenter, parallel-group study had an 8-week, single-blind, placebo baseline phase, after which patients were randomized to placebo (n = 102) or once-daily ESL 400 mg (n = 100… CONTINUE READING

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