Efficacy and safety of empagliflozin in combination with other oral hypoglycemic agents in patients with type 2 diabetes mellitus.

@article{Romera2016EfficacyAS,
  title={Efficacy and safety of empagliflozin in combination with other oral hypoglycemic agents in patients with type 2 diabetes mellitus.},
  author={Irene Romera and F. Javier Ampudia-Blasco and Antonio P{\'e}rez P{\'e}rez and Bernat Ari{\~n}o and Egon Pfarr and Sanja Giljanovic Kis and Ebrahim K. Naderali},
  journal={Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion},
  year={2016},
  volume={63 10},
  pages={519-526}
}
INTRODUCTION To analyze the efficacy and safety of empagliflozin combined with other oral hypoglycemic agents in patients with type 2 diabetes mellitus. METHODS Pooled analysis of three phase III trials in patients with type 2 diabetes mellitus (n=1,801) who received placebo or empagliflozin 10 or 25mg once daily for 24 weeks, in combination with metformin, metformin+sulphonylurea or pioglitazone ± metformin. RESULTS Empagliflozin significantly decreased HbA1c (adjusted mean reduction vs… CONTINUE READING

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