Efficacy and safety of dofetilide in patients with atrial fibrillation and atrial flutter

@article{Banchs2008EfficacyAS,
  title={Efficacy and safety of dofetilide in patients with atrial fibrillation and atrial flutter},
  author={Javier E Banchs and D. Wolbrette and S. Samii and Erica D. Penny-Peterson and P. Patel and S. Young and M. Gonz{\'a}lez and G. Naccarelli},
  journal={Journal of Interventional Cardiac Electrophysiology},
  year={2008},
  volume={23},
  pages={111-115}
}
  • Javier E Banchs, D. Wolbrette, +5 authors G. Naccarelli
  • Published 2008
  • Medicine
  • Journal of Interventional Cardiac Electrophysiology
  • BackgroundDofetilide, an IKr blocker has been demonstrated to be effective in terminating persistent atrial fibrillation and flutter (AF/AFL), and in maintaining sinus rhythm after direct current cardioversion (CV). It is not known, however, whether pharmacological conversion with dofetilide predicts maintenance of sinus rhythm. In addition, there is limited information comparing the efficacy of dofetilide in persistent versus paroxysmal AF/AFL.Methods and ResultsEighty consecutive patients… CONTINUE READING
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    References

    SHOWING 1-10 OF 25 REFERENCES
    Observations on the Safety and Effectiveness of Dofetilide in Patients With Paroxysmal Atrial Fibrillation and Normal Left Ventricular Function
    • 9
    • Highly Influential
    Dofetilide: a new class III antiarrhythmic agent
    • 56
    Electrophysiologic Effects of the New Class III Antiarrhythmic Drug Dofetilide in an Experimental Canine Model of Pacing-induced Atrial Fibrillation
    • 13
    Inter-relationships of atrial fibrillation and atrial flutter mechanisms and clinical implications.
    • 158
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