Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials.

@article{Umemura2016EfficacyAS,
  title={Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials.},
  author={Yutaka Umemura and Kazuma Yamakawa and Hiroshi Ogura and Hiroki Yuhara and Satoshi Fujimi},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2016},
  volume={14 3},
  pages={518-30}
}
UNLABELLED ESSENTIALS: Most anticoagulant therapy has failed to demonstrate a survival benefit in the overall sepsis population. We conducted separate meta-analyses of anticoagulant therapy in three different populations. Survival benefit was observed only in the septic disseminated intravascular coagulation (DIC) population. Further randomized controlled trials should focus on specific populations with septic DIC. SUMMARY BACKGROUND Although many preclinical trials have indicated the… CONTINUE READING

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A Proposal of the Modification of Japanese Society on Thrombosis and Hemostasis (JSTH) Disseminated Intravascular Coagulation (DIC) Diagnostic Criteria for Sepsis-Associated DIC.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis • 2018
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