Efficacy and safety of a single intra-articular injection of non-animal stabilized hyaluronic acid (NASHA) in patients with osteoarthritis of the knee.

@article{Altman2004EfficacyAS,
  title={Efficacy and safety of a single intra-articular injection of non-animal stabilized hyaluronic acid (NASHA) in patients with osteoarthritis of the knee.},
  author={Roy Altman and Christian {\AA}kermark and Andr{\'e} D. Beaulieu and Thomas J. Schnitzer},
  journal={Osteoarthritis and cartilage},
  year={2004},
  volume={12 8},
  pages={642-9}
}
OBJECTIVE Non-animal stabilized hyaluronic acid (NASHA) is a novel hyaluronan (HA) preparation with a 4-week intra-articular half-life. This study compared the efficacy of a single injection of NASHA with placebo in patients with osteoarthritis (OA) of the knee. DESIGN This was a 26-week randomized, double-blind, multicenter study of a single intra-articular knee injection with either NASHA or placebo (saline). Assessments included the Western Ontario McMasters Universities osteoarthritis… CONTINUE READING

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