Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary results of a 2-month prospective study.

@article{Villani2020EfficacyAS,
  title={Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary results of a 2-month prospective study.},
  author={Alessia Villani and Maria Carmela Annunziata and Eleonora Cinelli and Marianna Donnarumma and Massimo Milani and Gabriella Fabbrocini},
  journal={Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia},
  year={2020}
}
  • A. Villani, M. C. Annunziata, G. Fabbrocini
  • Published 1 September 2020
  • Medicine
  • Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia
BACKGROUND Acne vulgaris is a common and chronic skin disease that impacts on physical and psychological perceptions. Combination therapy with topical retinoids and antimicrobial agent is considered the preferred approach for most of the subjects affected by mild-to-moderate acne. A correct therapeutic management should include a prolonged treatment to ensure therapeutic success and to prevent recurrences. The aim of this study was to evaluate the efficacy and tolerability of a new topical gel… 

References

SHOWING 1-10 OF 15 REFERENCES
Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres.
TLDR
This study demonstrates that this fixed combination of hydroxypinacolone retinoate and retinol is an effective and safe option for the treatment of comedonal-papular, mild to moderate acne of the face.
Efficacy and safety of a 12-month treatment with a combination of hydroxypinacolone retinoate and retinol glycospheres as maintenance therapy in acne patients after oral isotretinoin.
  • V. Bettoli, S. Zauli, A. Virgili
  • Medicine
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia
  • 2017
TLDR
The findings seems to provide favorable evidence of the efficacy and the safety of this new product in the maintenance treatment after O.I. in patient with moderate acne.
The role of topical dermocosmetics in acne vulgaris
TLDR
The objective of this review was to provide new insights into the role of traditional and novel ingredients in dermocosmetics for the treatment of acne, based on the authors’ objective assessment of the published literature.
Skin Needling to Enhance Depigmenting Serum Penetration in the Treatment of Melasma
TLDR
The potential use of combining skin needling with rucinol and sophora-alpha compounds to achieve better results in melasma treatment compared to ruc inol and Sophora- alpha alone is suggested.
Update on etiopathogenesis and treatment of Acne
TLDR
A new armamentarium of drugs for the treatment of acne, including anti-androgens, insulin-like growth factor-1 inhibitors, peroxisome proliferator-activated receptor-modulators, acetylcholine inhibitors, topical retinoic acid metabolism-blocking agents, vitamin D analogues, antimicrobial peptides, interleukin-1β blockers and immunotherapy are some of the novel treatment options.
Adolescent female acne: etiology and management.
Management of acne: a report from a Global Alliance to Improve Outcomes in Acne.
Commentary: A UK primary care perspective on treating acne.
TLDR
This review provides an outline of current treatments for acne, which has a complex aetiology, involving abnormal keratinisation, hormonal function, bacterial growth, and immune hypersensitivity.
Acne: topical treatment.
Auto-classification of acne lesions using multimodal imaging.
TLDR
The results indicate a strong correlation between manual and auto-classified lesion counts (correlation coefficient >0.9) for both inflammatory and non inflammatory lesions this technology has the potential to eliminate the tedium of manual lesion counting, and provide an accurate, reproducible, and clinically relevant evaluation of acne lesions.
...
...