Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis

@article{Matkovic2010EfficacyAS,
  title={Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis},
  author={Zinka Matkovic and Vi{\vs}nja Živkovi{\'c} and Mirna Korica and Davor Plavec and Silva Pecanic and Neven Tudori{\'c}},
  journal={Phytotherapy Research},
  year={2010},
  volume={24}
}
The study was designed to investigate efficacy and safety of Astragalus membranaceus (AM) in the treatment of patients with seasonal allergic rhinitis (SAR). AM is an active component in the herbal and mineral complex (HMC) registered in Croatia as a food supplement Lectranal®. The study was designed as a 6‐weeks, double‐blind, placebo‐controlled clinical trial and conducted in 48 adult patients with a moderate to severe SAR. The treatment efficacy was evaluated by the mean change in the… 
Efficacy of Bimin decoction for patients with perennial allergic rhinitis: an open-label non-inferiority randomized controlled trial
TLDR
It is indicated that BMD is non-inferior to loratadine tablets and fluticasone nasal spray for AR patients with LQDCS and improves rhinitis-related quality of life.
Herbal Medicines for Allergic Rhinitis: a Systematic Review and Meta-analysis
TLDR
HM therapy is safe and provides better results than placebo in improving nasal symptoms and disease-specific quality of life in patients with AR and its beneficial effects are demonstrated only in less than 12 weeks of treatment.
Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model
TLDR
AM could reduce the secretion of inflammatory cytokines by increasing the level of CD4+ CD25+ Foxp3+ T cells and inhibiting the activation of the NF-κB and have no significant effect on mRNA of IκBα.
Complementary Therapies in Allergic Rhinitis
TLDR
This study found a high prevalence of herbal treatment usage for the relief of allergic rhinitis symptoms in Turkey.
Anti-Allergic Rhinitis Effects of Medicinal Plants and Their Bioactive Metabolites via Suppression of the Immune System: A Mechanistic Review
TLDR
A comprehensive review of up-to-date reports of studies on the anti-allergic rhinitis of several medicinal plants and their bioactive metabolites through suppression of the immune system are compiled and critically analyzed.
Phytomedicine in Otorhinolaryngology and Pulmonology: Clinical Trials with Herbal Remedies
TLDR
This review presents evidence-based clinical data with herbal remedies and tries to enlighten the question of efficacy and reliability of phytomedicine.
Cartilage protective and anti-analgesic effects of ALM16 on monosodium iodoacetate induced osteoarthritis in rats
TLDR
ALM16 markedly decreased the thickness of the paw edema and writhing response in a dose-dependent manner in mice and has a strong chondroprotective effect against the OA model in vitro and in vivo, likely attributed to its anti-inflammatory activity and inhibition of MMP production.
Astragaloside IV ameliorates allergic inflammation by inhibiting key initiating factors in the initial stage of sensitization
TLDR
The results suggest that AS-IV effectively ameliorates the progression of allergic inflammation by inhibiting key initiating factors, including TSLP and IL-33, and can be used to prevent and/or treat patients with ACD.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 24 REFERENCES
Treatment for seasonal allergic rhinitis by Chinese herbal medicine: a randomized placebo controlled trial.
TLDR
After eight weeks, the severity of nasal symptoms and non-nasal symptoms were significantly less in the active treatment group than in the control group, both for measurements made by patients and those by the practitioner.
Randomised controlled trial of butterbur and cetirizine for treating seasonal allergic rhinitis
TLDR
The effects of butterbur are similar to those of cetirizine in patients with seasonal allergic rhinitis when evaluated blindly by patients and doctors, and should be considered when the sedating effects of antihistamines must be avoided.
Herbal medicines for the treatment of allergic rhinitis: a systematic review.
  • R. Guo, M. Pittler, E. Ernst
  • Medicine
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • 2007
Butterbur Ze339 for the treatment of intermittent allergic rhinitis: dose-dependent efficacy in a prospective, randomized, double-blind, placebo-controlled study.
  • A. Schapowal
  • Medicine
    Archives of otolaryngology--head & neck surgery
  • 2004
OBJECTIVES To investigate whether the efficacy and safety of Butterbur extract Ze339 are related to dosage when administered to patients with intermittent allergic rhinitis. DESIGN Prospective,
Allergic rhinitis: continuous or on demand antihistamine therapy?
TLDR
It is questionable whether antihistamines should be administered on a continuous basis or upon demand, and the individualization of treatment according to the concrete characteristics of each patient seems to be the best approach, at least for the time being.
Immune System Effects of Echinacea, Ginseng, and Astragalus: A Review
TLDR
Although the margin of safety for these herbs is large, more research is needed to demonstrate the clear value of using herbs to improve resistance to infections, and 3 popular herbal immune stimulants that are often of interest to cancer patients are examined.
Complementary therapy in allergic rhinitis
TLDR
Of all the CAM therapies examined to treat allergic Rhinitis, some herbal therapies and antioxidants demonstrate a trend toward some clinical efficacy, but researchers have yet to determine how to integrate these CAM modalities into the general treatment paradigm of allergic rhinitis.
Preventive and curative effects of Gyokuheifu-san, a formula of traditional Chinese medicine, on allergic rhinitis induced with Japanese cedar pollens in guinea pig.
TLDR
Gyokuheifu-san (GHS), an herbal formula in traditional Chinese medicine that consolidates the superficial resistance to protect from invasion by external pathogenic influences, appears to have non-symptomatic and non-allopathic effects on allergic rhinitis.
...
1
2
3
...