Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis.

@article{Osterholm2011EfficacyAE,
  title={Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis.},
  author={Michael T. Osterholm and Nicholas S. Kelley and Alfred W. Sommer and Edward A. Belongia},
  journal={The Lancet. Infectious diseases},
  year={2011},
  volume={12 1},
  pages={
          36-44
        }
}
BACKGROUND No published meta-analyses have assessed efficacy and effectiveness of licensed influenza vaccines in the USA with sensitive and highly specific diagnostic tests to confirm influenza. METHODS We searched Medline for randomised controlled trials assessing a relative reduction in influenza risk of all circulating influenza viruses during individual seasons after vaccination (efficacy) and observational studies meeting inclusion criteria (effectiveness). Eligible articles were… CONTINUE READING
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Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis

  • MT Osterholm, NS Kelley, A Sommer, EA. Belongia
  • Lancet Infect Dis
  • 2011

MedImmune influenza update: 2011 national influenza vaccine summit

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