Efficacy and cost-effectiveness of autologous bone marrow transplantation in metastatic breast cancer. Estimates using decision analysis while awaiting clinical trial results.

@article{Hillner1992EfficacyAC,
  title={Efficacy and cost-effectiveness of autologous bone marrow transplantation in metastatic breast cancer. Estimates using decision analysis while awaiting clinical trial results.},
  author={Bruce E. Hillner and Thomas J. Smith and Christopher E. Desch},
  journal={JAMA},
  year={1992},
  volume={267 15},
  pages={2055-61}
}
OBJECTIVE To assess the efficacy and cost-effectiveness of standard chemotherapy and high-dose chemotherapy with autologous bone marrow transplantation (ABMT) in metastatic breast cancer. DESIGN Decision analysis model using a Markov process. SETTING Response and recurrence rates from the published literature for standard therapy and from case series of ABMT. Costs were based on local charges and on adjusted Medicare data. PATIENTS Hypothetical cohorts of women with metastatic breast… CONTINUE READING

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