Efficacy and Toxicity of Postoperative Temozolomide Radiochemotherapy in Malignant Glioma

@article{Kocher2005EfficacyAT,
  title={Efficacy and Toxicity of Postoperative Temozolomide Radiochemotherapy in Malignant Glioma},
  author={PD Martin Kocher and Sabine Kunze and H C Eich and Robert Semrau and R P Mueller},
  journal={Strahlentherapie und Onkologie},
  year={2005},
  volume={181},
  pages={157-163}
}
To evaluate the feasibility, safety and efficacy of daily temozolomide concurrent with postoperative radiotherapy in malignant glioma. From 11/1999 to 03/2003, n = 81 patients aged 15–72 years (median 52 years, Karnofsky score 80–100% in 83%) suffering from primary glioblastoma (n = 47), anaplastic astrocytoma (n = 6), anaplastic oligodendroglioma (n = 16), and recurrent glioma (n = 12) were treated. Patients with primary gliomas received a combination of postoperative radiotherapy (60 Gy/1.8… CONTINUE READING