Efficacy and Tolerability of Perospirone in Schizophrenia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
@article{Kishi2013EfficacyAT,
title={Efficacy and Tolerability of Perospirone in Schizophrenia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials},
author={T. Kishi and N. Iwata},
journal={CNS Drugs},
year={2013},
volume={27},
pages={731-741}
}BackgroundPerospirone is a second-generation antipsychotic (SGA) used only in Japan, and acts as a serotonin (5-HT)1A receptor partial agonist, 5-HT2A receptor inverse agonist, and dopamine (D)2, D4, and α1-adrenergic receptor antagonist. To our knowledge, no meta-analysis addressing the efficacy and effectiveness of perospirone in schizophrenia has been published to date.ObjectiveThe aim of the study was to identify the characteristics of perospirone by assessing the efficacy, discontinuation… CONTINUE READING
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