Efficacy and Safety of Ketamine in Patients with Complex Regional Pain Syndrome

@article{Azari2012EfficacyAS,
  title={Efficacy and Safety of Ketamine in Patients with Complex Regional Pain Syndrome},
  author={Pari Azari and David R. Lindsay and D. Briones and C. Clarke and T. Buchheit and Srinivas Pyati},
  journal={CNS Drugs},
  year={2012},
  volume={26},
  pages={215-228}
}
  • Pari Azari, David R. Lindsay, +3 authors Srinivas Pyati
  • Published 2012
  • Medicine
  • CNS Drugs
  • Despite being a recognized clinical entity for over 140 years, complex regional pain syndrome (CRPS) remains a difficult-to-treat condition. While there have been multiple therapies explored in the treatment of CRPS, NMDA antagonists such as ketamine continue to hold significant interest because of their potential ability to alter the central sensitization noted in chronic pain states. The objective of this review is to identify published literature for evidence of the efficacy and safety of… CONTINUE READING
    49 Citations

    Tables and Topics from this paper

    Paper Mentions

    Interventional Clinical Trial
    Reflex Sympathetic Dystrophy (RSD), Complex Regional Pain Syndrome (CRPS), Causalgia, and Fibromyalgia represent progressive systemic pain conditions which often worsen over time… Expand
    ConditionsCRPS - Complex Regional Pain Syndrome Type I, Fibromyalgia, RSD (Reflex Sympathetic Dystrophy)
    InterventionProcedure
    Effectiveness of complex regional pain syndrome treatment: A systematic review.
    • 8
    Treatment of Neuropathic Pain
    • 16
    Ketamine for Pain Management—Side Effects & Potential Adverse Events
    • 16
    • Highly Influenced
    Central Sensitization in Functional Chronic Pain Syndromes: Overview and Clinical Application.
    • Liz Bettini, K. Moore
    • Medicine
    • Pain management nursing : official journal of the American Society of Pain Management Nurses
    • 2016
    • 11
    Recent advances in the pharmacological management of acute and chronic pain.
    • 53
    • PDF
    [Ketamine for pain management].
    • 1
    Low‐Dose Ketamine for Postoperative Pain Management
    • 4
    Local Ketamine Improves Postoperative Analgesia After Third Molar Surgery.

    References

    SHOWING 1-10 OF 80 REFERENCES
    Treatment of complex regional pain syndrome: a review of the evidence
    • 146
    • PDF
    Multi-day low dose ketamine infusion for the treatment of complex regional pain syndrome.
    • 119
    • Highly Influential
    • PDF
    Efficacy of ketamine in anesthetic dosage for the treatment of refractory complex regional pain syndrome: an open-label phase II study.
    • 141
    • Highly Influential
    • PDF
    Ketamine in Chronic Pain Management: An Evidence-Based Review
    • 332
    • PDF
    A pilot open-label study of the efficacy of subanesthetic isomeric S(+)-ketamine in refractory CRPS patients.
    • 44
    • Highly Influential
    • PDF
    NMDA receptor antagonists for the treatment of neuropathic pain.
    • 102
    • Highly Influential
    • PDF
    The neurocognitive effects of 5 day anesthetic ketamine for the treatment of refractory complex regional pain syndrome.
    • S. Koffler, B. Hampstead, +4 authors R. Schwartzman
    • Psychology, Medicine
    • Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
    • 2007
    • 60
    • Highly Influential
    • PDF