Efficacy and Safety of Ketamine in Patients with Complex Regional Pain Syndrome

  title={Efficacy and Safety of Ketamine in Patients with Complex Regional Pain Syndrome},
  author={Pari Azari and David R. Lindsay and D. Briones and C. Clarke and T. Buchheit and Srinivas Pyati},
  journal={CNS Drugs},
  • Pari Azari, David R. Lindsay, +3 authors Srinivas Pyati
  • Published 2012
  • Medicine
  • CNS Drugs
  • Despite being a recognized clinical entity for over 140 years, complex regional pain syndrome (CRPS) remains a difficult-to-treat condition. While there have been multiple therapies explored in the treatment of CRPS, NMDA antagonists such as ketamine continue to hold significant interest because of their potential ability to alter the central sensitization noted in chronic pain states. The objective of this review is to identify published literature for evidence of the efficacy and safety of… CONTINUE READING
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