Efficacy and Safety of Ketamine in Patients with Complex Regional Pain Syndrome
@article{Azari2012EfficacyAS, title={Efficacy and Safety of Ketamine in Patients with Complex Regional Pain Syndrome}, author={Pari Azari and David R. Lindsay and Dean Briones and Collin Clarke and Thomas Buchheit and Srinivas Pyati}, journal={CNS Drugs}, year={2012}, volume={26}, pages={215-228} }
Despite being a recognized clinical entity for over 140 years, complex regional pain syndrome (CRPS) remains a difficult-to-treat condition. While there have been multiple therapies explored in the treatment of CRPS, NMDA antagonists such as ketamine continue to hold significant interest because of their potential ability to alter the central sensitization noted in chronic pain states. The objective of this review is to identify published literature for evidence of the efficacy and safety of…
63 Citations
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This work discusses sympathetic block, intravenous (IV) ketamine infusion, and peripheral nerve stimulation (PNS) in CRPS treatment and suggests PNS may help patients with CRPS pain limited to single nerve distributions.
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