Efficacy and Safety of Donepezil in Chinese Patients with Severe Alzheimer's Disease: A Randomized Controlled Trial.

@article{Jia2017EfficacyAS,
  title={Efficacy and Safety of Donepezil in Chinese Patients with Severe Alzheimer's Disease: A Randomized Controlled Trial.},
  author={Jian-Ping Jia and Cuibai Wei and Longfei Jia and Yi Tang and Junhua Liang and Aihong Zhou and Fangyu Li and Lu Shi and Rachelle Doody},
  journal={Journal of Alzheimer's disease : JAD},
  year={2017},
  volume={56 4},
  pages={
          1495-1504
        }
}
BACKGROUND Donepezil has been used worldwide for the treatment of severe Alzheimer's disease (AD). Whether it is also appropriate for severe AD in Chinese patients remains unknown. OBJECTIVE To determine whether donepezil is effective and tolerable for Chinese patients with severe AD. METHODS The present study was a 24-week, multicenter, double-blind, randomized, placebo-controlled, parallel-group study conducted at 38 investigational hospitals in China. Patients with severe AD were… CONTINUE READING

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