Efficacy and Safety of 6.25 mg t.i.d. Feverfew CO2-Extract (MIG-99) in Migraine Prevention — A Randomized, Double-Blind, Multicentre, Placebo-Controlled Study

@article{Diener2005EfficacyAS,
  title={Efficacy and Safety of 6.25 mg t.i.d. Feverfew CO2-Extract (MIG-99) in Migraine Prevention — A Randomized, Double-Blind, Multicentre, Placebo-Controlled Study},
  author={H. Diener and V. Pfaffenrath and J. Schnitker and M. Friede and H-H Henneicke-von Zepelin},
  journal={Cephalalgia},
  year={2005},
  volume={25},
  pages={1031 - 1041}
}
  • H. Diener, V. Pfaffenrath, +2 authors H-H Henneicke-von Zepelin
  • Published 2005
  • Medicine
  • Cephalalgia
  • The efficacy and tolerability of a CO2-extract of feverfew (MIG-99, 6.25 mg t.i.d.) for migraine prevention were investigated in a randomized, double-blind, placebo-controlled, multicentre, parallel-group study. Patients (N = 170 intention-to-treat; MIG-99, N = 89; placebo, N = 81) suffering from migraine according to International Headache Society criteria were treated for 16 weeks after a 4-week baseline period. The primary endpoint was the average number of migraine attacks per 28 days… CONTINUE READING
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    References

    SHOWING 1-10 OF 29 REFERENCES
    Herbal medicines in migraine prevention Randomized double-blind placebo-controlled crossover trial of a feverfew preparation.
    • 93
    Feverfew as a preventive treatment for migraine: a systematic review.
    • 57
    Propranolol for Migraine Prophylaxis
    • 58