Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget’s disease of bone

@article{Yoh2009EfficacyTA,
  title={Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget’s disease of bone},
  author={Kousei Yoh and Shinjiro Takata and Noriko Yoshimura and Jun Hashimoto},
  journal={Journal of Bone and Mineral Metabolism},
  year={2009},
  volume={28},
  pages={468-476}
}
This study evaluated the clinical efficacy of treatment with oral risedronate (17.5 mg once daily) for 8 weeks in 11 Japanese patients with Paget’s disease of bone (PDB). Risedronate suppressed the excessive bone turnover associated with PDB and improved several biochemical markers, including serum alkaline phosphatase (ALP), serum bone-specific ALP (BALP), urinary deoxypyridinoline (DPD), and urinary cross-linked N-telopeptide of type 1 collagen (NTX). These markers began to decrease within… CONTINUE READING
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