Efficacies of 5- and 14-day primaquine regimens in the prevention of relapses in Plasmodium vivax infections.

@article{Gogtay1999EfficaciesO5,
  title={Efficacies of 5- and 14-day primaquine regimens in the prevention of relapses in Plasmodium vivax infections.},
  author={N. J. Gogtay and Sanjiv Desai and K D Kamtekar and Vijay S. Kadam and Sudeshna S Dalvi and Nilima A. Kshirsagar},
  journal={Annals of tropical medicine and parasitology},
  year={1999},
  volume={93 8},
  pages={809-12}
}
Vivax malaria accounts for 80% of malaria cases in Mumbai (Bombay) and has high morbidity. In India, the standard treatment to prevent relapses of vivax malaria is a 5-day regimen of primaquine. However, between 1977 and 1997, the efficacy of this treatment declined from approximately 99% to 87%. The efficacy of the 5-day regimen was therefore compared with that of the 14-day regimen currently recommended by the World Health Organization, in Mumbai. The relapse rates observed, over a 6-month… CONTINUE READING

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