Effects on sleep of microdialysis of adenosine A1 and A2a receptor analogs into the lateral preoptic area of rats.

@article{Methippara2005EffectsOS,
  title={Effects on sleep of microdialysis of adenosine A1 and A2a receptor analogs into the lateral preoptic area of rats.},
  author={Melvi M Methippara and Sunil Kumar and Md Noor Alam and Ronald Szymusiak and Dennis McGinty},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2005},
  volume={289 6},
  pages={R1715-23}
}
Evidence suggests that adenosine (AD) is an endogenous sleep factor. The hypnogenic action of AD is mediated through its inhibitory A1 and excitatory A2A receptors. Although AD is thought to be predominantly active in the wake-active region of the basal forebrain (BF), a hypnogenic action of AD has been demonstrated in several other brain areas, including… CONTINUE READING