Effects on plasma lipids and fatty acid composition of very low fat diets enriched with fish or kangaroo meat

  title={Effects on plasma lipids and fatty acid composition of very low fat diets enriched with fish or kangaroo meat},
  author={Andrew J Sinclair and Kerin O'dea and Graeme A. Dunstan and Paul D. Ireland and Margaret Niall},
The effects of very low fat diets (<7% energy) enriched with different sources of long chain (C20 and C22) polyunsaturated fatty acids (PUFA) on plasma lipid levels and plasma fatty acids (PUFA) on plasma lipid levels and plasma fatty acid composition were studied in 13 healthy volunteers. Three diets provided 500 g/day of tropical Australian fish (rich in arachidonic acid and docosahexaenoic acid), southern Australian fish (rich in docosahexaenoic acid) or kangaroo meat (rich in linoleic and… 
The effect of dietary fat level and quality on plasma lipoprotein lipids and plasma fatty acids in normocholesterolemic subjects
Although the VLF vegetarian diet reduced both LDL- and HDL-cholesterol levels, the long-term effects of VF diets are unlikely to be deteterious since populations which habitually consume these diets have low rates of coronary heart disease.
Diets rich in lean beef increase arachidonic acid and long-chain ω3 polyunsaturated fatty acid levels in plasma phospholipids
The results showed that diets rich in lean beef increased the 20∶3ω6, 20∵4ω6 and the long-chain ω3 PUFA levels in the plasma PL and a high level of linoleic acid in diets richin lean beef prevented the rise in the Plasma level of 20∴3ω 6 and 20∷5ω3, two fatty acids known to antagonize the effects of 20⩽2ω6 on platelet aggregation.
Dietary manipulation of long-chain polyunsaturated fatty acids in the retina and brain of guinea pigs
The data suggest that the guinea pig has a reduced capacity for DHA synthesis from α-linolenic acid as compared with other mammals and Supplementation of guinea pigs diets with fish oil produced high retinal and brain DHA levels and prevented the accumulation of 22∶5n−6.
Consumption of Red Meat, but Not Cooking Oils High in Polyunsaturated Fat, Is Associated with Higher Arachidonic Acid Status in Singapore Chinese Adults
Red meat consumption, but not PUFA or PUFA-rich cooking oil, was associated with circulating AA suggesting that intake of pre-formed AA rather than LA is an important determinant of AA status.
Red Meat Consumption and Serum Lipids and Fatty Acids in Toddlers: Secondary Outcomes of a Randomized Controlled Trial
No effects associated with the intervention were found for total cholesterol, HDL cholesterol, total to HDL cholesterol ratio, or serum fatty acid composition, suggesting that the addition of ∼2 tablespoons/day of lean red meat to toddlers’ diets will likely not adversely affect serum lipids or fatty acids.
A role for omega-3 polyunsaturated fatty acid supplements in diabetic neuropathy.
A diet balanced in long-chain PUFAs modifies retinal lipid membranes in diabetes and prevents rod dysfunction, most likely secondary to the larger photoreceptor output.
Dietary arachidonic and linoleic acids: Comparative effects on tissue lipids
The data suggest that while the level of n−6 PUFA in the diet may have an important effect on tissue fatty acid composition, the type of n+6 PU FA in the diets could be of greater significance.
Lipoprotein composition and serum cholesterol ester fatty acids in nonwesternized melanesians
Marine n-3 fatty acids and linoleic acid showed the same potentially beneficial relationships with lipoproteins and apolipoproteins as in western populations.
Effects of dietary fats on prostanoid production and aortic and plasma fatty acid composition in rats
Only the most saturated fats, butter and beef tallow, had significant inhibitory effects on prostanoid production and platelet aggregation and were paralleled by similar decreases in aortic and plasma PL arachidonic acid content and an increase in eicosapentaenoic acid (EPA) and docosahexaenoic Acid (DHA).


Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol.
  • S. Grundy
  • Medicine
    The New England journal of medicine
  • 1986
A diet rich in monounsaturated fatty acids appears to be at least as effective in lowering plasma cholesterol as a diet low in fat and high in carbohydrate in short-term studies in which liquid diets are used and body weight is kept constant.
The effect of dietary essential fatty acids on the concentration of serum and liver lipids in the rat
It was concluded that linoleic acid and arachidonic acid had different and specific roles in lipid metabolism.
Increased proportion of arachidonic acid in plasma lipids after 2 weeks on a diet of tropical seafood.
Using capillary GLC, it is concluded that seafood from tropical waters, unlike seafood from colder waters, is a natural source of polyunsaturated fatty acids from both the omega 6 and omega 3 series.
The effect of sucrose content in high and low carbohydrate diets on plasma glucose, insulin, and lipid responses in hypertriglyceridemic humans.
The results of these studies demonstrate that high CHO-low fat diets, in general, tend to elevate plasma glucose, insulin, and TG concentrations and reduce HDL-Chol concentration in patients with endogenous hypertriglyceridemia and illustrate the important role that small variations in dietary sucrose can play in modulation of CHO and lipid metabolism.
Effect of high- and low-fiber diets on plasma lipids and insulin.
The results suggest that carbohydrates-induced hyperlipemia does not occur if the high carbohydrate diet is rich in dietary fiber, and furthermore that the insulin-stimulating potential of foods in a very high-carbohydrate diet is a critical determinant of the magnitude of carbohydrate-induced lipemia.
The analysis of polyunsaturated fatty acids in meat by capillary gas‐liquid chromatography
Polyunsaturated fatty acids (PUFA) of lean meat from domesticated and wild ruminants (cattle, sheep, goat, sambar deer and buffalo) and non-ruminants (pig, horse and kangaroo) have been examined by
Fatty acid composition of liver lipids during development of rat
The results suggested that the LCP in the rat liver triglycerides during the suckling period were derived from the long chain polyunsaturated acids in the dam's milk, rather than by synthesis from either 18∶2 or 18∷3 within the pups.
Metabolism of linoleic acid in the cat
Results show that there is no significant Δ6 desatur enzyme activity in the cat, whereas chain elongation and Δ5 desaturase enzymes are operative.
Marked Improvement in Carbohydrate and Lipid Metabolism in Diabetic Australian Aborigines After Temporary Reversion to Traditional Lifestyle
The major metabolic abnormalities of type II diabetes were either greatly improved or completely normalized in this group of Aborigines by relatively short reversal of the urbanization process.