Effects on inflammatory responses by the sphingoid base 4,8-sphingadienine.

  title={Effects on inflammatory responses by the sphingoid base 4,8-sphingadienine.},
  author={Evelien Rozema and Markus Binder and Murty A R C Bulusu and Valery N. Bochkov and Georg Krupitza and Brigitte Kopp},
  journal={International journal of molecular medicine},
  volume={30 3},
Sphingolipids (SLs) are a class of lipids, which are structural cell components involved in the regulation of cellular processes such as cell proliferation, differentiation, apoptosis and inflammation. Dietary SLs are enzymatically hydrolyzed in the gut lumen into metabolites, namely ceramides and sphingoid bases. The sphingoid base 4,8-sphingadienine (4,8-SD) is the metabolite of glucocerebrosides derived from plants that are part of… CONTINUE READING
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