Effects on Walker 256 tumour of carmustine associated with a cholesterol-rich microemulsion (LDE).

@article{Teixeira2004EffectsOW,
  title={Effects on Walker 256 tumour of carmustine associated with a cholesterol-rich microemulsion (LDE).},
  author={Raquel Teodoro Santos Teixeira and R. A. Curi and Raul C Maranh{\~a}o},
  journal={The Journal of pharmacy and pharmacology},
  year={2004},
  volume={56 7},
  pages={909-14}
}
A cholesterol-rich microemulsion that binds to low-density lipoprotein (LDL) receptors (LDE), after injection into the bloodstream, concentrates in neoplastic tissues that over-express those receptors. LDE can thus serve as a vehicle for drug targeting. It was shown that carmustine side effects are pronouncedly reduced when the drug is associated with LDE in cancer patients. In this study, the therapeutic action of LDE associated with carmustine was compared with that of the non-associated drug… CONTINUE READING
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