Effects of zuclomiphene in combination with triparanol and AY-9944 on developing rat CNS morphology and biochemistry

@article{Ramsey2004EffectsOZ,
  title={Effects of zuclomiphene in combination with triparanol and AY-9944 on developing rat CNS morphology and biochemistry},
  author={R. Ramsey and V. Fischer},
  journal={Acta Neuropathologica},
  year={2004},
  volume={39},
  pages={97-100}
}
  • R. Ramsey, V. Fischer
  • Published 2004
  • Chemistry, Medicine
  • Acta Neuropathologica
  • SummaryDeveloping rats were injected intraperitoneally twice weekly with a combination of three hypocholesterolemic agents: Zuclomiphene (formerly calledtrans-clomiphene; dosage, 30 mg/kg body weight), Triparanol (30 mg/kg body weight) and AY-9944 (3 mg/kg body weight). Treatment was initiated at 4 days of age. Biochemical and electron microscopic examination was conducted on animals sacrificed at 20 days of age. Cytoplasmic inclusion bodies were not seen in the CNS. Isolated edematous changes… CONTINUE READING
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    SHOWING 1-10 OF 19 REFERENCES
    Ultrastructural studies of the hepatic changes brought about by Clindamycin and Erythromycin in animals.
    • 45
    Ultrastructural study of neuronal cytoplasmic inclusions produced by hypocholesterolemic Drug, AY 9944
    • 21
    • Highly Influential
    Drug-induced phospholipidoses. II. Tissue distribution of the amphiphilic drug chlorphentermine.
    • 253
    Drug-induced phospholipidosis
    • 100