Effects of zinc-aspartate and zinc-glycinate in healthy rats and on reserpine-induced gastric lesions

@article{Barbarino1988EffectsOZ,
  title={Effects of zinc-aspartate and zinc-glycinate in healthy rats and on reserpine-induced gastric lesions},
  author={F. Barbarino and Elvira Tog{\^a}nel and Cornelia Brilinschi and I. Ciupe and I M Pop and I P Marinescu},
  journal={Biological Trace Element Research},
  year={1988},
  volume={16},
  pages={253-267}
}
Experimental studies performed on 227 rats showed that Zn-aspartate and Zn-glycinate administered ip lowered the incidence, number, and severity of the reserpine-induced gastric lesions ensuring significant protection indices. Histochemical methods revealed increased amount of mucosal glycoproteins. The activity of dehydrogenases involved in energy metabolism that modulates acid secretion in the parietal cells was depressed. RNA content in the chief cells as premises of pepsinogen synthesis… CONTINUE READING