Effects of xenoestrogens on the differentiation of behaviorally-relevant neural circuits

@article{Panzica2007EffectsOX,
  title={Effects of xenoestrogens on the differentiation of behaviorally-relevant neural circuits},
  author={Giancarlo Panzica and Carla Viglietti-Panzica and Elena Mura and Michael James Quinn and Emma T. Lavoie and Paola Palanza and Mary Ann Ottinger},
  journal={Frontiers in Neuroendocrinology},
  year={2007},
  volume={28},
  pages={179-200}
}
Effects of Xenoestrogens on the Differentiation of Behaviorally Relevant Neural Circuits in Higher Vertebrates
TLDR
The data presented here should stimulate a critical reanalysis of the way to determine the “safe” exposure levels to EDCs for wild species and humans, considering behavior and related neural circuits among the factors to be analyzed.
Reproductive Neuroendocrine Targets of Developmental Exposure to Endocrine Disruptors
TLDR
The available experimental animal and epidemiological data are supportive of a potential role of EDCs on alterations of neuroendocrine development, and on pubertal onset, as well as the majority of the studies summarized herein focus on laboratory animals.
Effects of estrous cycle and xenoestrogens expositions on mice nitric oxide producing system.
TLDR
It is revealed that the expression of neuronal NO synthase may vary according to the rapid variations of hormonal levels that take place during the estrous cycle, in accordance with the hypothesis that gonadal hormone activation of NO-cGMP pathway is important for mating behavior.
Bisphenol A: developmental toxicity from early prenatal exposure.
  • M. Golub, K. Wu, J. Donald
  • Medicine, Biology
    Birth defects research. Part B, Developmental and reproductive toxicology
  • 2010
TLDR
BPA research has actively integrated current knowledge of developmental biology, concepts of endocrine disruption, and toxicological research to provide a basis for human health risk assessment.
Effects of Perinatal Administration of Bisphenol A on the Neuronal Nitric Oxide Synthase Expressing System in the Hypothalamus and Limbic System of CD1 Mice
TLDR
Results indicate that BPA has a powerful effect on specific portions of the nNOS‐immunoreactive system belonging to the accessory olfactory system that are particularly important for the control of sexual behaviour and confirm that perinatal exposure to endocrine‐disrupting chemicals, in particular to BPA, may have a high impact on the organisation of specific neural pathways that can later affect complex behaviours and functions.
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