Effects of whole body <ce:sup loc=pre>56</ce:sup>Fe radiation on contextual freezing and Arc-positive cells in the dentate gyrus

@article{Raber2013EffectsOW,
  title={Effects of whole body <ce:sup loc=pre>56</ce:sup>Fe radiation on contextual freezing and Arc-positive cells in the dentate gyrus},
  author={Jacob Raber and Anti{\~n}o R. Allen and Susanna Rosi and Sourabh Sharma and Catherine A. Dayger and Matthew J. Davis and John Fike},
  journal={Behavioural Brain Research},
  year={2013},
  volume={246},
  pages={162-167}
}
The space radiation environment contains high-energy charged particles such as (56)Fe, which could pose a significant hazard to hippocampal function in astronauts during and after the mission(s). The mechanisms underlying impairments in cognition are not clear but might involve alterations in the percentage of neurons in the dentate gyrus expressing the plasticity-related immediate early gene Arc. Previously, we showed effects of cranial (56)Fe irradiation on hippocampus-dependent contextual… CONTINUE READING
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