Effects of water immersion on atrial natriuretic peptide release in humans.

@article{Epstein1989EffectsOW,
  title={Effects of water immersion on atrial natriuretic peptide release in humans.},
  author={Murray Epstein and Peter Norsk and Rodger Dale Loutzenhiser},
  journal={American journal of nephrology},
  year={1989},
  volume={9 1},
  pages={
          1-24
        }
}
Water immersion (WI) to the neck induces prompt increases in central blood volume, central venous pressure, and atrial distension. Since atrial distension is a major stimulus for atrial natriuretic peptide (ANP) release, WI constitutes a unique model to investigate the physiological importance of ANP in humans. All studies to date demonstrate that ANP increases during the 1st h of WI in hydrated subjects, rising 2.5- to 3-fold by the end of the 2nd or 3rd h. During recovery from WI, ANP returns… CONTINUE READING

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