Effects of volatile anesthetics on acetylcholine-induced relaxation in the rabbit mesenteric resistance artery.

@article{Akata1995EffectsOV,
  title={Effects of volatile anesthetics on acetylcholine-induced relaxation in the rabbit mesenteric resistance artery.},
  author={Takashi Akata and Mikio Nakashima and Kenji Kodama and Walter A. Boyle and Shosuke Takahashi},
  journal={Anesthesiology},
  year={1995},
  volume={82 1},
  pages={188-204}
}
BACKGROUND Vascular endothelium plays an important role in the regulation of vascular tone. Volatile anesthetics have been shown to attenuate endothelium-mediated relaxation in conductance arteries, such as aorta. However, significant differences in volatile anesthetic pharmacology between these large vessels and the small vessels that regulate systemic vascular resistance and blood flow have been documented, yet little is known about volatile anesthetic action on endothelial function in… CONTINUE READING

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