Effects of vitamin D3 metabolites on bone cell calcium transport

@article{Dziak1978EffectsOV,
  title={Effects of vitamin D3 metabolites on bone cell calcium transport},
  author={Rosemary Dziak},
  journal={Calcified Tissue Research},
  year={1978},
  volume={26},
  pages={65-70}
}
The vitamin D3 metabolite, 25-hydroxycholecalciferol, at concentrations of 0.01 to 10.0 μg/ml, decreased calcium uptake by isolated bone cells. The effect occurred within 1 min after the simultaneous addition of metabolite and45Ca. Lactic acid and ATP production by the cells was not affected. 24(R), 25-dihydroxycholecalciferol produced a similar decrease in calcium uptake. Vitamin D3 had no effect at concentrations from 0.01 to 10.0 μg/ml. No effect of 1,25-dihydroxycholecalciferol on calcium… CONTINUE READING
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Specific binding of 25-hydroxyvitamin D 3 in bone cell cytosol

  • A. M. Mellow, P. H. Stern
  • Pharmacologist 18, 233
  • 1976
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