Effects of vitamin D3 metabolites on bone cell calcium transport

  title={Effects of vitamin D3 metabolites on bone cell calcium transport},
  author={R. Dziak},
  journal={Calcified Tissue Research},
  • R. Dziak
  • Published 2005
  • Chemistry, Medicine
  • Calcified Tissue Research
  • SummaryThe vitamin D3 metabolite, 25-hydroxycholecalciferol, at concentrations of 0.01 to 10.0 μg/ml, decreased calcium uptake by isolated bone cells. The effect occurred within 1 min after the simultaneous addition of metabolite and45Ca. Lactic acid and ATP production by the cells was not affected. 24(R), 25-dihydroxycholecalciferol produced a similar decrease in calcium uptake. Vitamin D3 had no effect at concentrations from 0.01 to 10.0 μg/ml. No effect of 1,25-dihydroxycholecalciferol on… CONTINUE READING

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    • Open Access