Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis
@article{Reid2014EffectsOV, title={Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis}, author={I. Reid and M. Bolland and A. Grey}, journal={The Lancet}, year={2014}, volume={383}, pages={146-155} }
BACKGROUND
Findings from recent meta-analyses of vitamin D supplementation without co-administration of calcium have not shown fracture prevention, possibly because of insufficient power or inappropriate doses, or because the intervention was not targeted to deficient populations. Despite these data, almost half of older adults (older than 50 years) continue to use these supplements. Bone mineral density can be used to detect biologically significant effects in much smaller cohorts. We… CONTINUE READING
Topics from this paper
Paper Mentions
News Article
404 Citations
Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis.
- Medicine
- The lancet. Diabetes & endocrinology
- 2018
- 158
- PDF
The Effect of Calcium or Calcium and Vitamin D Supplementation on Bone Mineral Density in Healthy Males: A Systematic Review and Meta-Analysis.
- Medicine
- International journal of sport nutrition and exercise metabolism
- 2015
- 22
The combination effect of vitamin K and vitamin D on human bone quality: a meta-analysis of randomized controlled trials.
- Medicine
- Food & function
- 2020
- 1
Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency.
- Medicine
- Bone
- 2019
- 6
25‐Hydroxyvitamin D Threshold for the Effects of Vitamin D Supplements on Bone Density: Secondary Analysis of a Randomized Controlled Trial
- Medicine
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- 2018
- 44
- PDF
Effects of Vitamin D Supplementation on Bone Turnover Markers: A Randomized Controlled Trial
- Medicine
- Nutrients
- 2017
- 27
- PDF
Calcium intake and bone mineral density: systematic review and meta-analysis
- Medicine
- BMJ : British Medical Journal
- 2015
- 193
- PDF
Randomized controlled trial of vitamin D supplementation in older people to optimize bone health
- Medicine
- The American journal of clinical nutrition
- 2019
- 8
- PDF
The effect of high-dose vitamin D3 supplementation on bone mineral density in subjects with prediabetes
- Medicine
- Osteoporosis International
- 2017
- 8
- PDF
Vitamin D supplementation and fracture risk in adults: a new insight
- Medicine
- Osteoporosis International
- 2014
- 10
References
SHOWING 1-10 OF 63 REFERENCES
No significant effect on bone mineral density by high doses of vitamin D3 given to overweight subjects for one year
- Medicine
- Nutrition journal
- 2010
- 257
A pooled analysis of vitamin D dose requirements for fracture prevention.
- Medicine
- The New England journal of medicine
- 2012
- 676
- PDF
A Randomized Controlled Trial of Vitamin D Supplementation on Preventing Postmenopausal Bone Loss and Modifying Bone Metabolism Using Identical Twin Pairs
- Medicine
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- 2000
- 86
Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.
- Medicine
- JAMA
- 2005
- 1,465
- PDF
VIII: Meta-Analysis of the Efficacy of Vitamin D Treatment in Preventing Osteoporosis in Postmenopausal Women
- Medicine
- 2002
- 257
- PDF
Effects of calcium and vitamin D supplementation on hip bone mineral density and calcium-related analytes in elderly ambulatory Australian women: a five-year randomized controlled trial.
- Medicine
- The Journal of clinical endocrinology and metabolism
- 2008
- 114
- PDF
Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis
- Medicine
- The Lancet
- 2007
- 1,172
- PDF
Randomized Controlled Trial of the Effects of Calcium With or Without Vitamin D on Bone Structure and Bone‐Related Chemistry in Elderly Women With Vitamin D Insufficiency
- Medicine
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- 2008
- 85
Vitamin D supplementation and bone mineral density in early postmenopausal women.
- Medicine
- The American journal of clinical nutrition
- 2003
- 94
- PDF
Effectiveness and safety of vitamin D in relation to bone health.
- Medicine
- Evidence report/technology assessment
- 2007
- 648
- PDF