Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis

  title={Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis},
  author={I. Reid and M. Bolland and A. Grey},
  journal={The Lancet},
  • I. Reid, M. Bolland, A. Grey
  • Published 2014
  • Medicine
  • The Lancet
  • BACKGROUND Findings from recent meta-analyses of vitamin D supplementation without co-administration of calcium have not shown fracture prevention, possibly because of insufficient power or inappropriate doses, or because the intervention was not targeted to deficient populations. Despite these data, almost half of older adults (older than 50 years) continue to use these supplements. Bone mineral density can be used to detect biologically significant effects in much smaller cohorts. We… CONTINUE READING
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